Fifth seed Gilles Simon suffered a shock first-round defeat to Marco Cecchinato at the Croatia Open in Umag.
Cecchinato, ranked 105 in the world, progressed 6-1 3-6 6-1 against the French world number 36 for his first ATP Tour win since April 2016.
The Italian goes on to face Croatian wildcard Ivan Dodig, who pulled off a 6-4 7-6 (7/4) victory against Romania's Marius Copil.
In Monday's only first-round match at the Swedish Open in Bastad, Henri Laaksonen beat home wildcard Mikael Ymer 7-6 (7/5) 7-5 to book his place in the last 16 against third seed Pablo Cuevas .
Source: PA