Pakistan will be without Mohammad Asif for the two Twenty20 internationals against England later this month.
The two games will be played in Dubai on 19 and 20 February, but 27-year-old Asif is banned from entering the United Arab Emirates after being stopped for possession of opium in June 2008.
The Pakistan Cricket Board (PCB) had launched an appeal to try to have the suspension lifted but it has been turned down.
A PCB spokesman said: "We tried to get clearance for him from the authorities in Dubai so that he could play as he is our key bowler but it didn't work out."
Pakistan squad: Imran Nazir, Imran Farhat, Khalid Latif, Umar Akmal, Shoaib Malik (captain), Shahid Afridi, Yasir Arafat, Abdul Razzaq, Sarfraz Ahmed (wk), Umar Gul, Mohammad Talha, Fawad Alam, Wahab Riaz, Saeed Ajmal.